High- Versus Low-Dose Statin
نویسندگان
چکیده
منابع مشابه
Endothelial Effect of Statin Therapy at a High Dose Versus Low Dose Associated with Ezetimibe
BACKGROUND The effect of statins on the endothelial function in humans remains under discussion. Particularly, it is still unclear if the improvement in endothelial function is due to a reduction in LDL-cholesterol or to an arterial pleiotropic effect. OBJECTIVE To test the hypothesis that modulation of the endothelial function promoted by statins is primarily mediated by the degree of reduct...
متن کاملEfficacy of chronic statin therapy on major cardiac events after coronary artery bypass grafting: low-dose versus high-dose
Methods A total of 232 patients with previous CABG and chronic statin therapy were selected retrospectively and were divided into two groups according to a dosage of atorvastatin per day, e. g., 20 mg or 40 mg. Groups were compared for the major cardiac events and freedom from PCI by Kaplan Meier analysis as the primary end point. Patency of grafts including left internal thoracic artery (LITA)...
متن کاملHigh-Dose Statin for Every Stroke
Statins exert neuroprotective, microvascular, and antiinflammatory beneficial effects in animal stroke models, independent of their lipid-lowering capabilities. These are seen at the highest doses with a dose–response effect. Observational studies show that statin use is associated with improved outcome in patients with ischemic stroke, presumably a result of the pleiotropic effects suggested i...
متن کاملHigh-dose statin, not so IDEAL?
Tikkanen et al. (1) present an interesting post-hoc analysis of the IDEAL (Incremental Decrease in Endpoints Through Aggressive Lipid Lowering) study with a novel statistical method using all vascular rather than just the first cardiovascular events recorded, and they propose highly significant p values in support of using top-dose atorvastatin (80 mg/day) versus "standard" dose simvastatin (20...
متن کاملComparing Learners’ Writing Self Beliefs: High Achievers versus Low Achievers
The purpose of the present study was to compare writing high achievers and low achievers TEFL (teaching English as foreign language) learners’ writing self-beliefs. Subjects, based on their officially recorded scores on the writing course, were assigned in two 22-member groups of high and low achievers. The adapted English version of Mills’ and Péron’s (2008) questionnaire and the Foreign Langu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation
سال: 2018
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.118.034407